Comparison of school-based and home-based application of permethrin shampoo for the treatment of Pediculosis capatis - A pragmatic cluster-randomized trial
Pediatric Infectious Disease Society of the Philippines Journal
; : 4-11, 2015.
Article
em En
| WPRIM
| ID: wpr-633504
Biblioteca responsável:
WPRO
ABSTRACT
@#<p style="text-align justify;"><strong>BACKGROUND:
</strong> Pediculosis continues to be a common yet neglected public health problem especially in children. Trials to test for effectiveness for head lice interventions are heterogeneous, and a recent systematic review recommended the use of cluster randomization and centralized administration (e.g. school) of permethrin for pediculosis trials.</p> <p style="text-align justify;"><strong>OBJECTIVE:
</strong> To compare the effectiveness of a school-based to a home-based intervention using permethrin 1% shampoo in treating pediculosis capitis. </p> <p style="text-align justify;"><strong>METHODS:
</strong> We conducted a pragmatic, cluster-randomized trial at the Makati Elementary School. All Grade Four students (n = 211), belonging to a total of five class sections, were invited to participate in the study. Students with a known allergic reaction to permethrin 1% shampoo, with open wounds on the scalp, or were absent on Days 1 or 10 of the intervention period were excluded. The five class sections were randomized to receive permethrin 1% shampoo to be applied either in school, or at home. The students were classified as having none, light, medium, or heavy infestation prior to Day 1 and after Day 10 treatment. Prevalence, incidence, and treatment outcomes were measured.</p> <p style="text-align justify;"><strong>RESULTS:
</strong> The baseline prevalence of pediculosis capitis was 58.4%. General characteristics of students were similar between groups. No significant clustering in pediculosis classification was observed. The school-based group had the same prevalence in pediculosis at Days 1 and 10, had no incident cases, and were limited to light infestation by Day 10, but had no treatment success outcomes. The home-based group had increased prevalence by Day 10, poor compliance with Day 1 and 10 shampoo, incident cases, although it registered a higher treatment success rate.</p> <p style="text-align justify;"><strong>CONCLUSION:
</strong> Compared to standard home based intervention, a school-based strategy resulted in less incident cases (0% vs. 37%), reduction in pediculosis severity (p = 0.007), and higher compliance (100% vs. 58.3%). Control of pediculosis in this specific community is largely warranted because of its high prevalence rate of 59.7%.</p> <p style="text-align justify;"> </p>
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Índice:
WPRIM
Assunto principal:
Infestações por Piolhos
/
Pediculus
/
Couro Cabeludo
/
Instituições Acadêmicas
/
Estudantes
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Saúde Pública
/
Resultado do Tratamento
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Permetrina
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Hipersensibilidade
Tipo de estudo:
Clinical_trials
Limite:
Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Pediatric Infectious Disease Society of the Philippines Journal
Ano de publicação:
2015
Tipo de documento:
Article