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Apoptosis and proliferation of peripheral blood lymphocytes from primary nephrotic syndrome children and effects of dexamethasone on them / 实用儿科临床杂志
Article em Zh | WPRIM | ID: wpr-638346
Biblioteca responsável: WPRO
ABSTRACT
Objective To explore the apoptosis and proliferation of peripheral blood lymphocytes(PBLs) from primary nephrotic syndrome(PNS) and effects of dexamethasone(Dex) on them.Methods Minimal change NS(MCNS), non-minimal change NS(NMCNS) and healthy children were involved in this study. PBLs were cultured in vitro with Dex or PHA+Dex or without PHA and Dex. Apoptosis of PBLs was measured by propidium iodide(PI) staining; The effects of Dex at different concentrons on PBLs′proliferation were investigated by 3H-TdR incorporation.Results The apoptotic rate of vacuity group in MCNS was lower compared with NMCNS and healthy controls(P
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Journal of Applied Clinical Pediatrics Ano de publicação: 2004 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Journal of Applied Clinical Pediatrics Ano de publicação: 2004 Tipo de documento: Article