Analysis on high risk human papillomavirus genotypes among male outpatients in Suzhou area / 国际检验医学杂志

ABSTRACT

Objective To understand the infection status ,genotype distribution of high risk human papillomavirus (HR-HPV ) infection and its relation with diseases among male outpatients in Suzhou area .Methods The HR-HPV DNA genotyping detection in 1432 male outpatients was performed by using multiple polymerase chain reaction and flow cytometry fluorescence hybridization technique .Results The total infection rate of HR-HPV was 25 .6% (367/1432) ,single infection ,double infection and multiple infection accounted for 72 .20% ,21 .25% and 0 .65% respectively .The HR-HPV infection rate had no statistical difference among different age groups(χ2 =1 .912 ,P=0 .861) .The top five places of HR-HPV subtypes were HPV-16 ,HPV-52 ,HPV-58 ,HPV-18 and HPV-59 .HPV-16 ,HPV-52 ,HPV-58 infections were most common among the age groups of ＜20 years old ,＞ 60 years old and ＜20 years old ,and the top 3 diseases related to HR-HPV were verruca ,urethritis and balanitis .Conclusion HPV-16 is the most common HR-HPV infection type in male outpatients ,followed by HPV-52 and-58 .The HR-HPV infection has a certain age specificity and is related to male verruca ,urethritis and balanitis .