Correlation between Chromosomal Abnormality and Cell Morphology with Myelodysplastic Syndrome Patients / 现代检验医学杂志
Journal of Modern Laboratory Medicine
; (4): 71-73, 2017.
Article
em Zh
| WPRIM
| ID: wpr-663446
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the correlation between morphological abnormalities and abnormal myelodysplastic syn-dromes(MDS)cloning.Methods 82 cases of MDS were collected with complete FISH and morphological abnormalities. The relationship between MDS cell morphology and chromosome abnormality was investigated.Results 45 cases of chromo-somal abnormalities were found,and +8 were the most frequent chromosomal abnormalities.8 cases were +8,-5 and 5q-were 6,20q-were 7,-7 and 7q-were 5,complex karyotypes(>3 abnormalities)were 6.There were statistically significant differences in the proportion of primordial cells,megakaryocyte dysplasia,megakaryocyte abnormalities between karyotype abnormal group and karyotype normal group(P<0.05).There were statistically significant differences in the proportion of abnormal karyotype among high risk group and low risk group,the low risk group and medium risk group(P<0.05).Con-clusion The chromosomal abnormalities of MDS patients would be related to morphological changes.
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WPRIM
Idioma:
Zh
Revista:
Journal of Modern Laboratory Medicine
Ano de publicação:
2017
Tipo de documento:
Article