The inhibition of citral on platelet aggregation induced by arachidonic acid / 实用医学杂志

ABSTRACT

Objective To discuss the effects of citral on adhesion and aggregation of platelets induced by AA(arachidonic acid)for clinical treatment and prevention of thrombotic diseases. Methods Evaluation of citral on adhesion and aggregation of platelets induced by AA were processed by multimode reader. Results There was significant difference in inhibiting aggregation of platelets between the control group and the drug group in a concen-tration of 111 μg/mL of citral.A series of concentration of citral also contributed the same effect in concentration of 25,30,35 mmol/L of AA. Conclusions The most effective concentration of citral is 111 μg/mL in inhibiting aggregation of platelets.The citral has an effect in inhibiting aggregation of platelets.