Target organs function damage in elderly patients with H type hypertension and its association with blood pressure variability / 重庆医学
Chongqing Medicine
; (36): 740-743,747, 2018.
Article
em Zh
| WPRIM
| ID: wpr-691858
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WPRO
ABSTRACT
Objective To investigate the target organs function damage in elderly patients with H type hypertension and its association with blood pressure variability.Methods Ninety-two patients with H type hypertension in the Affiliated Hospital of Inner Mongolia Medical University from January 2014 to January 2016 were collected as the observation group and contemporaneous 135 elderly patients with non-H type hypertension were collected as the control group.The main observation indicators included 24 h systolic/diastolic blood pressure variability,24 h average systolic/diastolic blood pressure,glomerular filtration rate(GFR),serum creatinine,24 h urinary microalbumin,carotid intima-media thickness and left ventricular mass index.Results Compared with the control group,24 h systolic blood pressure variability,24 h diastolic blood pressure variability,creatinine,24 h urinary microalbumin,carotid intima-media thickness and left ventricular mass index in the observation group were significantly increased(P<0.05);GFR was significantly decreased (P<0.05).The multiple linear regression analysis showed that 24 h systolic blood pressure variability was the factors affecting GFR (P<0.05);24 h systolic blood pressure variability was the factor affecting~the creatinine level (P<0.05);24 h systolic blood pressure,24 h systolic blood pressure variability and 24 h diastolic blood pressure variability were the influence factors of carotid intima-media thickness (P<0.05);24 h systolic blood pressure variability was the influence factor of left ventricular mass index (P<0.05).Conclusion The target organs function damage in the patients with H type hypertension is serious,and the blood pressurevariability enlargement is the influencing factor of target organs function damage.
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Idioma:
Zh
Revista:
Chongqing Medicine
Ano de publicação:
2018
Tipo de documento:
Article