Safety and efficacy of plasmakinetic in divided enucleation of the prostate for benign prostatic hyperplasia with prostate volumes of over 80 ml / 国际外科学杂志

ABSTRACT

Objective To evaluate the safety and efficacy of bipolar transurethral plasmakinetic enucleation of the prostate (PKEP) with PKRP for benign prostatic hyperplasia (BPH) with prostate volumes over 80 ml.Methods A total of 78 patients of BPH with prostate volume more than 80 ml were retrospectively analysed to either PKEP (n =41) or PKRP (n =37).All patients were assessed preoperatively and followed up of clinic at the 3rd,6th,and 12 th month postoperatively.Baseline characteristics of the patients,intraoperative events (operation time,bleeding volume),postoperative events (bladder irrigation time,catheter time) and postoperative effect evaluation (IPSS score,QOL score and Qmax) were recorded.t test was used for measurement data expressed by ((x) ± s) among groups.And chi-square test was used for Enumeration data expressed by rate(％) between the two groups.Results The operation time,the decrease of hemoglobin,irrigation time and the catheter time in the PKEP and PKRP were (100.7 ±31.2),(150.1 ±30.3) min,(1.1 ±0.5),(2.1 ±0.8) g/dl,(16.9 ±4.3),(31.8 ± 8.3) h,(33.4 ± 11.2),(51.7 ± 18.6) h,respectively.Those indexes in the PKEP group were significantly better than those in the PKRP group (P ＜ 0.05).The baseline values and postoperative outcome indices of PKEP group at the 3rd,6th,and 12 th month were IPSS (28.01 ± 5.31),(15.01 ± 3.62),(8.01 ±2.30),(7.83±2.11)、QOL(4.5 ±0.8),(3.5 ±0.6),(1.3 ±0.4),(1.1 ±0.5)、Qmax(6.21 t2.09),(13.24 ± 2.31),(15.33 ± 2.44),(17.65 ± 3.21) mL/s,residual urine volume (75.02 ± 25.21),(10.87 ±6.16),(10.55 ± 5.21),(9.97 ± 5.63) ml.All the indices after 3 months of operation were improved compared with baseline values (P ＜ 0.05).The incidence of complications in PKEP group (17.1 ％,7/41) was lower than that in PKRP group (27.0％,10/17) (P =0.288).Conclusion PKEP is a safe and efficient treatment of BPH patients with prostate volume more than 80 ml.Compared with PKRP,PKEP provides less risk of hemorrhage and shorter catheter time,the operation time,irrigation time.