Etiology and risk factors for meningitis and/or bacteremia after craniotomy for patients with glioma / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 410-414, 2018.
Article
em Zh
| WPRIM
| ID: wpr-693831
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To evaluate the incidence and microbiological profile of meningitis and/or bacteremia after craniotomy in patients with glioma and analyze the risk factors relevant to postoperative meningitis.Methods:
All demographic data,etiological data and clinical data for hospitalized patients who underwent craniotomy in Dept.of Neurosurgery of Peking Union Medical College Hospital between Jan.2013 to Dec.2017 were recorded.Results:
The incidence of post-craniotomy meningitiswas 7.73%,bacteremia was 2.21% and meningitis combined with bacteremia was 1.10%.The positive rate for cerebrospinal fluid culture was 78.57%.Among the 11 cases of meningitis,20 bacteria were detected,and the most common gram-positive bacteria wereepidermal Staphylococcus (3 case,15.0%),and hemolytic Staphylococcus (3 case,15.0%);the most common gram-negative one was Klebsiella pneumoniae (2 case,10.0%).Among the 5 cases of bacteremia,Klebsiella pneumoniae was the most common one (3 cases,60.0%).Most of the gram-positive bacteria were sensitive to vancomycin and were resistant to penicillin G.Most of the gram-negative bacteria were sensitive to the 3rd generation of cephalosporin and meropenem.Among all the 16 patients,13 were good in prognosis (81.3%) while 3 (18.8%) were poor in prognosis,with 2 deaths and 1 discharged automatically.Among the 11 patients with meningitis,7 patients (63.6%) were male and 7(63.6%) were older than 50 years old.The lesionsin the 6 patients located in the frontal lobe (54.5%) and the glioma in 6 patients was at WHO grade Ⅳ (54.5%).Three patients were diagnosed as diabetes before the surgery (27.3%).Conclusion:
Postoperative meningitis and bacteremia can occur in patients with glioma.The pathogens and drug susceptibility are different.The risk factors for meningitis after craniotomy should be concerned before making a treatment plan.
Texto completo:
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Índice:
WPRIM
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
Zh
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2018
Tipo de documento:
Article