L-carnitine and type 2 diabetes mellitus / 中国糖尿病杂志

ABSTRACT

The occurrence and development of type 2 diabetes mellitus(T2DM) are related to abnormal energy metabolism.L-carnitine,as one of the most important drugs to improve energy metabolism,has gradually been in a hot research in recent years.It can prevent cell lipid peroxidation,prevent oxidation by free radical scavenging,promote long-chain fatty acids into mitochondria for β-oxidation and increase lipid metabolism and improving diabetic complications.It can also decrease insulin resistance (IR),and lower fasting blood glucose (FBG).L-carnitine may have certain inhibitory effect on the development of T2DM.Early application of L-carnitine may improve the complication of T2DM diabetes,and provide a new way for the treatment of T2DM.