Advances in the pathogenesis of long non-coding RNA in glioma / 中国医师杂志

ABSTRACT

Glioma is one of the most common intracranial tumors.Long non-coding RNA(lncRNA) cannot be translated into proteins but has many important effects on bio-functions and diseases of human beings.The functions of lncRNA includes epigenetic regulation,transcription regulation,lncRNA-miRNA interation,being precursor of miRNA and these functions play important role in pathogenesis of glioma,lncRNA has many regulatory effects on the proliferation,invasion and metastasis of glioma cells,and plays a guiding role in the diagnosis and treatment of glioma.lncRNA influence the proliferation,migration and invasion of glioma and the study of lncRNA mean a lot in the treatment of patients with glioma.