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A study on the IFIH1 gene polymorphism in children with type 1 diabetes in Tianjin area / 中华内分泌代谢杂志
Article em Zh | WPRIM | ID: wpr-709904
Biblioteca responsável: WPRO
ABSTRACT
The blood samples of 102 type 1 diabetic children aged under 15 years and 127 normal children were collected and their genomic DNAs were extracted. The single nucleotide polymorphisms rs1990760 and rs35744605 of interferon induced with helicase C domain 1(IFIH1)gene were detected. The results showed that the allele of IFIH1 rs35744605 in diabetes group and control group was the wild type G allele. The frequency of IFIH1 rs1990760 A allele in diabetes group was higher than that in control group(22. 1% vs 13. 0% ,P=0. 015), suggesting that IFIH1 rs1990760 A allele is associated with type 1 diabetes in Tianjin area.
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Endocrinology and Metabolism Ano de publicação: 2018 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Endocrinology and Metabolism Ano de publicação: 2018 Tipo de documento: Article