Extent of central lymph node dissection for papillary thyroid carcinoma in the isthmus
Annals of Surgical Treatment and Research
; : 229-234, 2018.
Article
em En
| WPRIM
| ID: wpr-714539
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
The incidence of papillary thyroid carcinoma (PTC) arising from the isthmus is low; however, these tumors have aggressive clinical and pathological features. Moreover, the existing guidelines regarding the extent of surgery for this type of tumor are unclear.METHODS:
This study enrolled 282 patients who underwent total thyroidectomy with bilateral central lymph node dissection. The patients were divided into 2 groups based on the location of the median line of the PTC. Group I included patients in whom the median line was located between the lateral margins of the trachea; group II included all others. We compared the 2 groups and conducted a multivariate analysis to assess risk factors for contralateral node metastasis from a PTC arising from the isthmus.RESULTS:
Patients in group I had significantly higher frequencies of extrathyroidal extension and central lymph node metastasis. Group I also had a higher frequency of contralateral node metastasis, and a tumor size >1.0 cm was identified as an independent risk factor for contralateral node metastasis among patients in this group.CONCLUSION:
Bilateral central lymph node dissection could be considered for patients with isthmic PTCs >1.0 cm in size who have clinically suspicious node metastasis.Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Glândula Tireoide
/
Tireoidectomia
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Traqueia
/
Neoplasias da Glândula Tireoide
/
Incidência
/
Análise Multivariada
/
Fatores de Risco
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Excisão de Linfonodo
/
Linfonodos
/
Metástase Neoplásica
Tipo de estudo:
Etiology_studies
/
Guideline
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Annals of Surgical Treatment and Research
Ano de publicação:
2018
Tipo de documento:
Article