Factors Influencing the Background Parenchymal Enhancement in Follow-Up Breast MRI after Adjuvant Endocrine Therapy
Investigative Magnetic Resonance Imaging
; : 99-106, 2015.
Article
em En
| WPRIM
| ID: wpr-71457
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
To investigate factors influencing the evaluation of background parenchymal enhancement (BPE) at follow-up breast magnetic resonance imaging (MRI) after adjuvant endocrine therapy. MATERIALS ANDMETHODS:
One hundred twelve women with breast cancer and MRI of the contralateral unaffected breast before and after endocrine therapy were identified. Two readers in consensus performed blinded side-by-side comparison of BPE (minimal, mild, moderate, and marked) before and after therapy with categorical scales. Age, body mass index, menopausal status, treatment regimen (selective estrogen receptor modulator or aromatase inhibitor), chemotherapy, follow-up duration, BPE at baseline MRI, MRI field strength before and after therapy, and recurrence were analyzed for their influences on decreased BPE.RESULTS:
Younger age, premenopausal status, treatment with selective estrogen receptor modulator, MRI field strength, and moderate or marked baseline BPE were significantly associated with decreased BPE. In multivariate analysis, MRI field strength and baseline BPE showed a significant association.CONCLUSION:
MRI field strength and baseline BPE before and after therapy were associated with decreased BPE at post-therapy, follow-up MRI.Palavras-chave
Texto completo:
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Índice:
WPRIM
Assunto principal:
Recidiva
/
Pesos e Medidas
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Mama
/
Neoplasias da Mama
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Imageamento por Ressonância Magnética
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Aromatase
/
Índice de Massa Corporal
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Análise Multivariada
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Seguimentos
/
Moduladores de Receptor Estrogênico
Tipo de estudo:
Guideline
/
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
En
Revista:
Investigative Magnetic Resonance Imaging
Ano de publicação:
2015
Tipo de documento:
Article