Catheter-Related Trichosporon asahii Bloodstream Infection in a Neutropenic Patient with Myelodysplastic Syndrome / 감염과화학요법
Infection and Chemotherapy
; : 138-143, 2018.
Article
em En
| WPRIM
| ID: wpr-721996
Biblioteca responsável:
WPRO
ABSTRACT
Because primary antifungal prophylaxis is widely used for immunocompromised hosts, the incidences of unusual fungal infections have increased. Trichosporon asahii has emerged as an important life-threatening opportunistic systemic pathogen because of the increased use of cytotoxic or immunosuppressant agents, along with high mortality rates. Here, we describe a case of catheter-related T. asahii bloodstream infection with multiple septic skin nodules in both the arms and legs of the patient who was in the neutropenic period after allogeneic stem cell transplantation for myelodysplastic syndrome treated with prophylactic ciprofloxacin and itraconazole. We successfully treated her with intravenous voriconazole for more than a month without any complications. Clinicians should consider breakthrough Trichosporon infections when clinical progress in an immunocompromised patient with unexplained infection signs and symptoms does not improve despite proper treatment with antibiotics or various antifungal agents. In addition, voriconazole can be a good treatment choice for achieving better treatment results and prognosis.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Braço
/
Prognóstico
/
Pele
/
Síndromes Mielodisplásicas
/
Trichosporon
/
Ciprofloxacina
/
Incidência
/
Mortalidade
/
Hospedeiro Imunocomprometido
/
Fungemia
Tipo de estudo:
Incidence_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Infection and Chemotherapy
Ano de publicação:
2018
Tipo de documento:
Article