Histochemical Findings of Soleus in Relation to the Severity of Injury and Duration of Exercise in Sciatic Nerve Injured Rats
Journal of the Korean Academy of Rehabilitation Medicine
; : 727-734, 2003.
Article
em Ko
| WPRIM
| ID: wpr-722926
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the histopathological findings of soleus muscle in relation to the severity of injury and the duration of treadmill exercise in rats with sciatic nerve damage.METHOD:
Sciatic nerve of seventy rats was compressed with haemostatic forceps. The experimental group was divided into 4 subgroups according to the intensity and duration of injury group 1, first degree compression for 5 seconds; group 2, first degree for 30 seconds; group 3, third degree for 5 seconds; and group 4, third degree for 30 seconds. Treadmill exercise was done for either 30 minutes or 2 hours a day, 5 days a week for 4 weeks. Histochemical study of soleus was done before nerve compression and 1 week, 4 weeks after compression.RESULTS:
The fiber diameter of soleus was larger in the experimental group at 4 weeks (p<0.05). The intensity of injury had greater impact on the recovery of fiber diameter than the duration. Thirty minute exercise was seen to have a earlier recovery of fiber diameter than 2 hours.CONCLUSION:
These results may provide the basic data to clarify the neurological recovery in relation to the severity of injury, and to help establishing adequate duration of exercise after nerve damage.Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Nervo Isquiático
/
Instrumentos Cirúrgicos
/
Músculo Esquelético
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
Ko
Revista:
Journal of the Korean Academy of Rehabilitation Medicine
Ano de publicação:
2003
Tipo de documento:
Article