A Cytogenetic Analysis of Abortus with Spontaneous Abortion
Journal of Genetic Medicine
; : 62-66, 2009.
Article
em Ko
| WPRIM
| ID: wpr-72325
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Chromosomal abnormalities of abortuses have been used to investigate common etiologies of spontaneous abortion, but the frequencies and types of spontaneous abortions have demonstrated considerable variation among different countries and races. MATERIALS ANDMETHODS:
A cytogenetic analysis of 75 abortuses was performed at GenDix, Inc. from January 2006 to December 2007.RESULTS:
The frequency of chromosome abnormalities in abortuses was 32.0% (24/75 cases). Among the chromosomal abnormalities, trisomy was present in 62.5% (15/24 cases) of cases and the most frequent trisomy was trisomy 21 with an occurrence rate of 26.6% (4/15 cases). The following was trisomy 22 (3/15 cases) and trisomy 20 (2/15 cases). The average maternal age for abnormal karyotypes was 34.3+/-3.3.CONCLUSION:
Cytogenetic analysis of abortus is important for diagnosis and genetic counseling of patients with spontaneous abortion.Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Trissomia
/
Cromossomos Humanos Par 20
/
Cromossomos Humanos Par 22
/
Aborto Espontâneo
/
Aberrações Cromossômicas
/
Idade Materna
/
Síndrome de Down
/
Análise Citogenética
/
Citogenética
/
Cariótipo Anormal
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
Ko
Revista:
Journal of Genetic Medicine
Ano de publicação:
2009
Tipo de documento:
Article