Progress of diagnosis and treatment of light chain amyloidosis / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 57-60, 2019.
Article
em Zh
| WPRIM
| ID: wpr-732685
Biblioteca responsável:
WPRO
ABSTRACT
Systemic amyloidosis is caused by misfolding of heavy or light chain in immune globulin and extracellular deposition of proteins as amyloid fibrils. The most common form is light chain amyloidosis, which results in dysfunction of vital organs. Specific biomarkers and amyloid imaging can prompt organ dysfunction at early diagnosis and prevent the organ failure at end stage. Combination therapy is the direction of light chain amyloidosis therapy in the future. The studies on the target therapy concerning clone light chain and amyloid deposition, and new drugs that can control light chain gathering and hydrolysis are under exploration. This paper reviews the treatment progress of light chain amyloidosis.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
Zh
Revista:
Journal of Leukemia & Lymphoma
Ano de publicação:
2019
Tipo de documento:
Article