Evaluation of the efficacy of an attenuated live vaccine based on virulent porcine reproductive and respiratory syndrome virus 2 in young pigs / 대한수의학회지
Korean Journal of Veterinary Research
; : 137-141, 2018.
Article
em En
| WPRIM
| ID: wpr-741511
Biblioteca responsável:
WPRO
ABSTRACT
The efficacy of the CA-2-MP120 vaccine, a cell culture-attenuated strain of virulent porcine reproductive and respiratory syndrome virus (PRRSV), was assessed in pigs. Despite the persistence of viremia in all vaccinated animals during the immunization period, the virus was not detected in vaccinated pigs following challenge. Furthermore, no pigs in the vaccinated group shed PRRSV nasally, orally or rectally throughout the experiment. Moreover, histopathological lung and lymph node lesions in the immunized group were much milder than those in the unimmunized and challenged group. These results indicated that CA-2-MP120 can provide effective protection against virulent wildtype PRRSV-2.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Suínos
/
Viremia
/
Vacinas Atenuadas
/
Imunização
/
Vacinação
/
Resultado do Tratamento
/
Vírus da Síndrome Respiratória e Reprodutiva Suína
/
Síndrome Respiratória e Reprodutiva Suína
/
Pulmão
/
Linfonodos
Limite:
Animals
Idioma:
En
Revista:
Korean Journal of Veterinary Research
Ano de publicação:
2018
Tipo de documento:
Article