Extracorporeal Life Support in Adult Patients with Hematologic Malignancies and Acute Circulatory and/or Respiratory Failure / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
; : 25-31, 2019.
Article
em En
| WPRIM
| ID: wpr-742337
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
The primary goal of this study was to characterize the clinical outcomes of adult patients with hematologic malignancies (HM) who were treated with extracorporeal membrane oxygenation (ECMO) support when conventional treatments failed.METHODS:
In this retrospective, observational study at a tertiary medical center, we reviewed the clinical course of 23 consecutive patients with HM requiring ECMO who were admitted to the intensive care unit at Asan Medical Center from March 2010 to April 2015.RESULTS:
A total of 23 patients (8 female; median age, 44 years; range, 29–51 years) with HM and severe acute circulatory and/or respiratory failure received ECMO therapy during the study period. Fourteen patients received veno-arterial ECMO, while 9 patients received veno-venous ECMO. The median ECMO duration was 104.7 hours (range, 37.1–221 hours). Nine patients were successfully weaned from ECMO. The in-hospital mortality rate was 91.1% (21 of 23). There were complications in 3 patients (cannulation site bleeding, limb ischemia, and gastrointestinal bleeding).CONCLUSION:
ECMO is a useful treatment for patients with circulatory and/or pulmonary failure. However, in patients with HM, the outcomes of ECMO treatment results were very poor, so it is advisable to carefully decide whether to apply ECMO to these patients.Palavras-chave
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Índice:
WPRIM
Assunto principal:
Insuficiência Respiratória
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Oxigenação por Membrana Extracorpórea
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Estudos Retrospectivos
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Mortalidade
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Mortalidade Hospitalar
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Neoplasias Hematológicas
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Extremidades
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Estudo Observacional
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Hemorragia
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Unidades de Terapia Intensiva
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
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Female
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Humans
Idioma:
En
Revista:
The Korean Journal of Thoracic and Cardiovascular Surgery
Ano de publicação:
2019
Tipo de documento:
Article