The Role of Activated Hepatic Stellate Cells in Liver Fibrosis, Portal Hypertension and Cancer Angiogenesis / 대한간학회지
The Korean Journal of Hepatology
; : 309-319, 2007.
Article
em Ko
| WPRIM
| ID: wpr-7449
Biblioteca responsável:
WPRO
ABSTRACT
Although hepatic stellate cells, which are liver specific pericytes, have been recognized within the vasculature of the sinusoid for more than one hundred years, the biology and function of these cells is unclear. Recent studies have highlighted the key role of stellate cells in a number of fundamental processes that include wound healing/fibrosis, vasoregulation, and vascular remodeling/angiogenesis. In the liver, these processes are particularly important in the development of cirrhosis, portal hypertension and cancer. This article highlights the recent advances in our understanding of the biology of hepatic stellate cells and discusses some of the recently-ascribed functions that are relevant to liver fibrosis, portal hypertension and cancer angiogenesis.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Comunicação Celular
/
Pericitos
/
Hipertensão Portal
/
Células de Kupffer
/
Cirrose Hepática
/
Neoplasias Hepáticas
/
Neovascularização Patológica
Limite:
Humans
Idioma:
Ko
Revista:
The Korean Journal of Hepatology
Ano de publicação:
2007
Tipo de documento:
Article