mTORC1 signaling in hepatic lipid metabolism
Protein & Cell
; (12): 145-151, 2018.
Article
em En
| WPRIM
| ID: wpr-756988
Biblioteca responsável:
WPRO
ABSTRACT
The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and physiological processes in different organs or tissues. Dysregulation of mTOR signaling has been implicated in many human diseases including obesity, diabetes, cancer, fatty liver diseases, and neuronal disorders. Here we review recent progress in understanding how mTORC1 (mTOR complex 1) signaling regulates lipid metabolism in the liver.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Transdução de Sinais
/
Biologia Celular
/
Metabolismo dos Lipídeos
/
Lipogênese
/
Alvo Mecanístico do Complexo 1 de Rapamicina
/
Fígado
/
Metabolismo
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Protein & Cell
Ano de publicação:
2018
Tipo de documento:
Article