Amoebic Encephalitis Caused by Balamuthia mandrillaris
Journal of Pathology and Translational Medicine
; : 327-331, 2019.
Article
em En
| WPRIM
| ID: wpr-766037
Biblioteca responsável:
WPRO
ABSTRACT
We present the case of a 71-year-old man who was diagnosed with amoebic encephalitis caused by Balamuthia mandrillaris. He had rheumatic arthritis for 30 years and had undergone continuous treatment with immunosuppressants. First, he complained of partial spasm from the left thigh to the left upper limb. Magnetic resonance imaging revealed multifocal enhancing nodules in the cortical and subcortical area of both cerebral hemispheres, which were suggestive of brain metastases. However, the patient developed fever with stuporous mentality and an open biopsy was performed immediately. Microscopically, numerous amoebic trophozoites, measuring 20 to 25 µm in size, with nuclei containing one to four nucleoli and some scattered cysts having a double-layered wall were noted in the background of hemorrhagic necrosis. Based on the microscopic findings, amoebic encephalitis caused by Balamuthia mandrillaris was diagnosed. The patient died on the 10th day after being admitted at the hospital. The diagnosis of amoebic encephalitis in the early stage is difficult for clinicians. Moreover, most cases undergo rapid deterioration, resulting in fatal consequences. In this report, we present the first case of B. mandrillaris amoebic encephalitis with fatal progression in a Korean patient.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Febre Reumática
/
Espasmo
/
Coxa da Perna
/
Biópsia
/
Encéfalo
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Imageamento por Ressonância Magnética
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Extremidade Superior
/
Diagnóstico
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Encefalite
/
Trofozoítos
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
/
Humans
Idioma:
En
Revista:
Journal of Pathology and Translational Medicine
Ano de publicação:
2019
Tipo de documento:
Article