Progress on medication-related osteonecrosis of the jaw / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 568-572, 2018.
Article
em Zh
| WPRIM
| ID: wpr-772457
Biblioteca responsável:
WPRO
ABSTRACT
Medication-related osteonecrosis of the jaw (MRONJ) is a severe complication of bisphosphonates (BPs) or other targeted agent therapies. MRONJ appears as exposed bone, pus, and swelling in the oral and maxillofacial regions. However, neither surgery nor conservative therapy can eliminate symptoms thoroughly. In addition to BPs, several antiresorptive and antiangiogenic agents, such as denosumab and bevacizumab, as well as targeted agents, such as sunitinib and temsirolimus, can cause osteonecrosis of the jaw according to the literature. This review aims to summarize the research progress on these new drugs.
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WPRIM
Assunto principal:
Inibidores da Angiogênese
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Usos Terapêuticos
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Difosfonatos
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Tratamento Farmacológico
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Conservadores da Densidade Óssea
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Osteonecrose da Arcada Osseodentária Associada a Difosfonatos
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Denosumab
Limite:
Humans
Idioma:
Zh
Revista:
West China Journal of Stomatology
Ano de publicação:
2018
Tipo de documento:
Article