Research advance in circular RNAs / 生理学报
Acta Physiologica Sinica
; (6): 613-624, 2019.
Article
em Zh
| WPRIM
| ID: wpr-777149
Biblioteca responsável:
WPRO
ABSTRACT
Circular RNAs (circRNAs) are a class of endogenous, covalently closed, single-stranded RNA without 3'-poly(A) and 5'-cap structures. CircRNAs are characterized by universality, diversity, stability and conservation, and have been found to regulate mammalian transcription and be translated into proteins. In this review, we summarized the biogenesis, classification, expression, distribution, biological functions and regulation of circRNAs. In addition, we discussed the association of circRNAs with diseases and the methods for identification and characterization of circRNAs. Finally, we speculated the application prospect and research direction of circRNAs.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pesquisa
/
RNA
/
Genética
Limite:
Animals
Idioma:
Zh
Revista:
Acta Physiologica Sinica
Ano de publicação:
2019
Tipo de documento:
Article