Clinical trials tracking nonalcoholic fatty liver disease: Noninvasive measures / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 2501-2504, 2018.
Article
em Zh
| WPRIM
| ID: wpr-778930
Biblioteca responsável:
WPRO
ABSTRACT
Nonalcoholic fatty liver disease (NAFLD) has become one of the research hotspots in the field of liver disease. However, so far, no drugs have been approved by the U.S. Food and Drug Administration for the treatment of nonalcoholic steatohepatitis, which brings opportunities and challenges to the clinical trials on the treatment of NAFLD. Liver histology is currently considered a reliable surrogate endpoint for tracking the progression of NAFLD, but its invasiveness has limited the development of drugs for the treatment of NAFLD. In recent years, some noninvasive measurement methods have gradually been used as secondary or exploratory endpoints in existing clinical trials.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2018
Tipo de documento:
Article