Spontaneous Retroperitoneal Hemorrhage Caused by Idiopathic Acquired Hemophilia A Misdiagnosed as a Delayed Traumatic Hematoma: A Case Report
Journal of Acute Care Surgery
; (2): 72-75, 2019.
Article
em En
| WPRIM
| ID: wpr-785887
Biblioteca responsável:
WPRO
ABSTRACT
Acquired hemophilia A (AHA) is a rare disease where typically coagulation factor VIII is inhibited by autoantibodies. It occurs in patients with no personal or familial history of bleeding. In this case study a 61-year-old male presented with a huge psoas hematoma. He had no history of bleeding disorders. He was initially diagnosed with delayed traumatic hematoma. Despite conservative and surgical treatments, coagulopathy was not resolved and postoperative bleeding continued. Consequently, coagulation factor tests were performed and showed reduced activity of factor VIII (2.7%). In addition, factor VIII inhibitor was detected. The patient was diagnosed with AHA and administered recombinant factor VIII for 3 days which resulted in the cessation of bleeding. AHA can lead to a life-threatening hemorrhage, and needs to be considered in differential diagnoses in any patients presenting with unexplained and repeated bleeding, where there is no personal or familial history of bleeding disorders.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Autoanticorpos
/
Transtornos da Coagulação Sanguínea
/
Fatores de Coagulação Sanguínea
/
Fator VIII
/
Doenças Raras
/
Diagnóstico Diferencial
/
Hematoma
/
Hemofilia A
/
Hemorragia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
Journal of Acute Care Surgery
Ano de publicação:
2019
Tipo de documento:
Article