Surgical Experience of Cortical Dysplasia in Patient with Intractable Epilepsy

ABSTRACT

Cortical dysplasia is a rare developmental disorder developed from a defect of neuronal migration. It is characterized by disruption of the normal cortical lamination by abnormal large nerve cells and large astrocytes in the cerebral mantle, often causing intractable seizures. The advance of magnetic resonance imaging enables us to make an in-vivo diagnosis of cortical dysplasia. The authors present a case of 23-months-old girl, who underwent temporal lobectomy for medically intractable seizures.