Orchidopexy increases the levels of serum anti-Müllerian hormone and inhibin B in cryptorchidism patients / 中华男科学杂志
National Journal of Andrology
; (12): 713-716, 2017.
Article
em Zh
| WPRIM
| ID: wpr-812890
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WPRO
ABSTRACT
Objective@#To investigate the levels of serum anti-Müllerian hormone (AMH) and inhibin B (INHB) in patients with unilateral cryptorchidism before and after orchidopexy.@*METHODS@#This study included 58 cases of unilateral cryptorchidism treated by orchidopexy and 32 healthy controls. Before and at 6 months after surgery, we measured the length and circumference of the penis, the volume of the undescended testis, and levels of serum AMH and INHB.@*RESULTS@#There were statistically significant differences between the unilateral cryptorchidism and healthy control groups in the levels of serum AMH ([102.80 ± 17.35 vs 108.76 ± 13.64] ng/ml, P0.05; INHB: [75.76 ± 5.94] vs [77.63 ± 5.99] pg/ml, P>0.05). No remarkable differences were observed between the unilateral cryptorchidism and healthy control groups in the preoperative penile length ([2.05 ± 0.23] vs [2.11 ± 0.22] cm, P>0.05), penile circumference ([3.91 ± 0.23] vs [3.99 ± 0.20] cm, P>0.05) and volume of the undescended testis ([0.45 ± 0.02] vs [0.46 ± 0.02] ml, P>0.05), or in the postoperative penile length ([2.09 ± 0.23] vs [2.16 ± 0.22] cm, P>0.05), penile circumference ([4.00 ± 0.25] vs [3.98 ± 0.19] cm, P>0.05) and volume of the undescended testis ([0.45 ± 0.02] vs [0.45 ± 0.02] ml, P>0.05). Compared with the baseline, the cryptorchidism patients showed markedly increased levels of serum AMH ([102.80 ± 17.35] vs [109.76 ± 17.25] ng/ml, P<0.05) and INHB ([70.24 ± 5.73] vs [75.76 ± 5.94] pg/ml, P<0.05) after orchidopexy.@*CONCLUSIONS@#Orchidopexy can elevate the levels of serum AMH and INHB and protect the testicular function of cryptorchidism patients.
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Índice:
WPRIM
Assunto principal:
Tamanho do Órgão
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Patologia
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Pênis
/
Período Pós-Operatório
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Cirurgia Geral
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Sangue
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Estudos de Casos e Controles
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Criptorquidismo
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Hormônio Antimülleriano
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Período Pré-Operatório
Tipo de estudo:
Observational_studies
Limite:
Humans
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Male
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2017
Tipo de documento:
Article