The effects of handgrip exercise in reducing peripherally inserted central catheter-related venous thrombosis:a Meta-analysis / 中国实用护理杂志

ABSTRACT

Objective To evaluate the effects on reduction of peripherally inserted central catheter-related venous thrombosis by hand grip exercise. Methods A detailed search was performed to identify literature about the impact of handgrip exercise on peripherally inserted central catheter-related venous thrombosis, using the Cochrane Library and the databases of PubMed, CINAHL, Embase, CNKI, WanFang and CBM. The meta-analysis or descriptive review were performed after two authors in-dependently searching databases,extracting data and assessing quality of included studies. Results Seven RCTs were included in a total of 789 patients. Meta-analysis showed the effectiveness of handgrip exercise on reduction of peripherally inserted central catheter-related venous thrombosis ( RR=0.27, 95% CI 0.17-0.42, P＜0.01); and improving vein maximum velocity ( WMD=6.53, 95% CI 3.34-9.73, P＜0.01) and time-mean flow velocity ( WMD=6.05, 95% CI 3.24-8.87, P＜0.01). Conclusions Handgrip exercise can improve axillary vein blood flow parameters and reduce peripherally inserted central catheter-related venous thrombosis. Due to a small number of included studies and heterogeneity of indicators,multi-centered,high-quality RCTs with large sample size are needed in the future to assess the effect of handgrip exercise in PICC patients.