Molecular characteristics of meningiomas
Journal of Pathology and Translational Medicine
; : 45-63, 2020.
Article
em 0
| WPRIM
| ID: wpr-834527
Biblioteca responsável:
WPRO
ABSTRACT
Meningioma is the most common primary intracranial tumor in adults. The grading of meningioma is based on World Health Organization criteria, which rely on histopathological features alone. This grading system is unable to conclusively predict the clinical behavior of these tumors (i.e., recurrence or prognosis in benign or atypical grades). Advances in molecular techniques over the last decade that include genomic and epigenomic data associated with meningiomas have been used to identify genetic biomarkers that can predict tumor behavior. This review summarizes the molecular characteristics of meningioma using genetic and epigenetic biomarkers. Molecular alterations that can predict meningioma behavior may be integrated into the upcoming World Health Organization grading system.
Texto completo:
1
Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
0
Revista:
Journal of Pathology and Translational Medicine
Ano de publicação:
2020
Tipo de documento:
Article