Hormone Therapy in Postmenopausal Women
Journal of the Korean Medical Association
; : 377-384, 2005.
Article
em Ko
| WPRIM
| ID: wpr-84017
Biblioteca responsável:
WPRO
ABSTRACT
Until the results of Women's Health Initiative (WHI) was released in July 2002, hormone replacement after menopause had been thought to be the most effective way to manage menopause-related symptoms and to prevent longterm related diseases including osteoporosis, cardiovascular disease, and Alzheimer's disease. A significant increase in breast cancer incidence (by 26%) brought the early termination of the WHI study. After an assessment of the overall risk-benefit ratio, the WHI investigators failed to demonstrate beneficial effects of the combined hormone therapy. This article reviews the results of several large randomized controlled studies and discusses the risks and benefits of hormone therapy.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Osteoporose
/
Pesquisadores
/
Neoplasias da Mama
/
Menopausa
/
Doenças Cardiovasculares
/
Incidência
/
Saúde da Mulher
/
Medição de Risco
/
Doença de Alzheimer
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Journal of the Korean Medical Association
Ano de publicação:
2005
Tipo de documento:
Article