Noise-induced hearing loss and cochlea neurotransmitters: Recent progress / 第二军医大学学报

ABSTRACT

Being the primary neurons in the auditory system, spiral ganglion neurons form the afferent synapse with hair cells and play a critical role in the analysis and integration of hearing. Many kinds of neurotransmitters can be found in the cochlear and they have different effects under both physiological and pathological conditions with complicated mechanism. This article reviews the characters of some transmitters in cochlear, such as glutamate, ATP, dopamine and GABA, and their roles in noise-induced hearing loss, hoping to provide more clues for research and therapy of inner ear diseases.