Quality control of Chinese materia medica injection based on Q-marker-- Taking salvianolic acids for injection as an example / 中草药
Chinese Traditional and Herbal Drugs
; (24): 4663-4672, 2019.
Article
em Zh
| WPRIM
| ID: wpr-850816
Biblioteca responsável:
WPRO
ABSTRACT
Based on the concept of quality marker (Q-marker) and the application of Q-marker in traditional Chinese medicine, the quality control methods of Chinese materia medica injections were put forward, taking salvianolic acids for injection as an example. Through the analysis of components, efficacy and pharmacokinetics, it has been identified that the Q-marker of salvianolic acids for injection were salvianolic acid B, rosmarinic acid, lithospermic acid, salvianolic acid D, and salvianolic acid Y. The quality control system of multi-index content determination, fingerprint, near infrared on-line control, and biological quality control was established with Q-marker as the core. It provides a reference for the new ideas of quality control of Chinese materia medica injection.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2019
Tipo de documento:
Article