Study on chemical constituents of Callicarpa kwangtungensis / 中草药

ABSTRACT

Objective To study the ethyl acetate-soluble chemical constituents of Callicarpa kwangtungensis. Methods The chemical constituents were isolated by column chromatography on silica gel, ODS, Sephadex LH-20, and MPLC. Their chemical structures were elucidated on the basis of special analysis. Results Sixteen compounds were isolated and identified as carpeside B (1), loliolide (2), (3S,6E,10R)-10-β-D-glucopyranosyloxy-3,11-dihydroxy-3,7,11-trimethyldodeca-1,6-dine (3), lanceolatin A (4), daidzein (5), secroisolariciresinol (6), (7S,8R)-4,9,9'-trihydroxy-3,3'-dimethoxy-7,8-dihydrobenzofuran-1'-propylneolignan (7), silybin A (8), isosilybin A (9), isosilybin B (10), 2,3-dehydrosilyhin (11), silychristin A (12), silychristin B (13), isosilychristin (14), silydianin (15), and nigaichigoside F2 (16). Conclusion Compounds 4-15 are isolated from the genus Callicarpa for the first time.