Research progress on synthesis of phloretin derivatives / 中草药

ABSTRACT

Phloretin is a kind of natural dihydrochalcone from the root bark, fruits, and leaves of the apple tree. It’s also found in a variety of plants. Phloretin has remarkable curative effect in anti-inflammatory, antibacterial, antitumor, and other biological activities. So it has a wide range of application prospects. The derivatization of phloretin contributes to the improvement of its biological activity and water solubility. This paper reviews the progress of the derivatization of phloretin and provides a reference for its research and utilization.