Neurological disease and microbiota-gut-brain axis / 国际儿科学杂志

ABSTRACT

The gut microbiota play an important role in the bidirectional interactions between the gut and the nervous system, which is called the microbiota-gut-brain axis.The short-chain fatty acids, neurotransmitters, Vagal nerve and the hypothalamus-pituitary-adrenal axis are different ways of affecting neurological diseases, including Alzheimer′s disease, Parkinson′s disease, depression disease; childhood autism and neonatal encephalopathy.Based on the studies of neurological diseases, this paper analyzes the role of gut microbiota in diseases, and provides a modern consideration for the further research and clinical application of microbiota-gut-brain axis.