Progress in the encoding characteristics and mechanisms of hippocampal neural assemble sequences in spatial memory / 生理学报
Acta Physiologica Sinica
; (6): 793-803, 2020.
Article
em Zh
| WPRIM
| ID: wpr-878227
Biblioteca responsável:
WPRO
ABSTRACT
The formation, consolidation and retrieval of spatial memory depend on sequential firing patterns of place cells assembling in the hippocampus. Theta sequences of place cells during behavior play a role in acquisition of spatial memory, trajectory prediction and decision making. In awake rest and slow wave sleep, place cell sequences occur during the sharp wave-ripples (SWRs), called "replay", which is crucial for memory consolidation and retrieval. In this review, we summarize the functional significances of theta sequences and SWRs replay sequences and the mechanism of these sequences. We also discuss the relationship between theta and replay sequences with the formation of spatial memory. We propose the research direction in this field in future and aim to provide new ideas for related researches.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Sono
/
Vigília
/
Memória Espacial
/
Hipocampo
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Acta Physiologica Sinica
Ano de publicação:
2020
Tipo de documento:
Article