Progress of studies on anti-breast tumor mechanism of alkaloids / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 312-319, 2021.
Article
em Zh
| WPRIM
| ID: wpr-878976
Biblioteca responsável:
WPRO
ABSTRACT
Breast tumor has become one of the malignant tumors with the highest incidence, and is a serious threat to human health, especially to women. Chemotherapy is an important anti-breast tumor therapy, which can be used in almost every stage of breast tumor therapy alone or in the combination with surgery and radiation therapy. Alkaloids are a kind of ubiquitous natural products, and important active components of various medicinal plants. A large number of studies have shown that alkaloids could exert an anti-breast tumor effect by inhibiting proliferation, metastasis and angiogenesis, resisting mitosis, promoting apoptosis and autophagy, and triggering cell cycle arrest. The extensive anti-breast tumor effect makes alkaloids an important candidate drug source. This paper reviews the anti-breast tumor mechanism of natural products of alkaloids.
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Assunto principal:
Autofagia
/
Neoplasias da Mama
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Apoptose
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Linhagem Celular Tumoral
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Proliferação de Células
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Alcaloides
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Pontos de Checagem do Ciclo Celular
Limite:
Female
/
Humans
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2021
Tipo de documento:
Article