Inhibition of indoxyl sulfate-induced intrarenal renin-angiotensin system activation: targeting the aryl hydrocarbon receptor
Translational and Clinical Pharmacology
; : 114-116, 2017.
Article
em En
| WPRIM
| ID: wpr-87968
Biblioteca responsável:
WPRO
ABSTRACT
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complications.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Sistema Renina-Angiotensina
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Receptores de Hidrocarboneto Arílico
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Insuficiência Renal Crônica
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Indicã
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Rim
Idioma:
En
Revista:
Translational and Clinical Pharmacology
Ano de publicação:
2017
Tipo de documento:
Article