Hyperhomocysteinemia, a Biochemical Tool for Differentiating Ischemic and Nonischemic Central Retinal Vein Occlusion during the Early Acute Phase
Korean Journal of Ophthalmology
; : 86-91, 2015.
Article
em En
| WPRIM
| ID: wpr-88447
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: The purpose of the study was to differentiate ischemic central retinal vein occlusion (CRVO) from nonischemic CRVO during the early acute phase using plasma homocysteine as a biochemical marker. METHODS: Fasting plasma homocysteine, serum vitamin B12, and folate levels were measured in 108 consecutive unilateral elderly adult (age >50 years) ischemic CRVO patients in the absence of local and systemic disease and compared with a total of 144 age and sex matched nonischemic CRVO patients and 120 age and sex matched healthy control subjects. RESULTS: Homocysteine level was significantly increased in the patients with ischemic CRVO in comparison with nonischemic CRVO patients (p = 0.009) and also in comparison with control subjects (p 0.1). CONCLUSIONS: Hyperhomocysteinemia can be regarded as useful in differentiating nonischemic and ischemic CRVO during the early acute phase in absence of local and systemic disease in the elderly adult (age >50 years) population.
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Assunto principal:
Fatores de Tempo
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Oclusão da Veia Retiniana
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Biomarcadores
/
Estudos de Casos e Controles
/
Doença Aguda
/
Estudos Prospectivos
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Seguimentos
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Hiper-Homocisteinemia
/
Diagnóstico Diferencial
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2015
Tipo de documento:
Article