Optimization of Ethanol Extraction Technology of Mongolian Medicine Naru- 3 / 中国药房
China Pharmacy
; (12): 1988-1994, 2021.
Article
em Zh
| WPRIM
| ID: wpr-886583
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:To optim ize ethanol extraction technology of Mongolian medicine Naru- 3. METHODS :The L 9(34) orthogonal design was used to optimize ethanol extraction technology of Mongolian medicine Naru- 3 with solid-liquid ratio ,ethanol volume fraction and extraction time as factors ,using comprehensive scores for the contents of benzoylaconitine ,benzoylneoaconitine, benzoylhypoaconitine,aconitine,neoaconitine,hypoaconitine,piperine and gallic acid as indexes. RESULTS :The optimal ethanol extraction technology was that solid-liquid ratio of 1∶10(g/mL),ethanol volume fraction of 75%,extracting for 1.5 h. After 3 times of validation tests ,average contents of above 8 components in ethanol extract from Naru- 3 were 1.69,1.48,14.69,0.28, 0.05,0.08,26.01,17.33 mg/g(RSDs were 0-4.96%,n=3),respectively. Average comprehensive score was 19.03(RSD=1.42%, n=3). CONCLUSIONS :The optimal ethanol extraction technology of Mongolian medicine Naru- 3 is stable and feasible.
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WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2021
Tipo de documento:
Article