New bisabolane-type phenolic sesquiterpenoids from the marine sponge Plakortis simplex / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 626-631, 2021.
Article
em En
| WPRIM
| ID: wpr-888791
Biblioteca responsável:
WPRO
ABSTRACT
Six new bisabolane-type phenolic sesquiterpenoids, including plakordiols A-D (1-4), (7R, 10R)-hydroxycurcudiol (5) and (7R, 10S)-hydroxycurcudiol (6) were isolated from the marine sponge Plakortis simplex collected from the South China Sea. Their structures were determined based on extensive analysis of spectroscopic data. Their configurations were assigned by coupling constant analysis, NOESY correlations, and the modified Mosher's method. Furthermore, their cytotoxic and antibacterial activities were evaluated.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Oceano Pacífico
/
Estrutura Molecular
/
China
/
Plakortis
/
Sesquiterpenos Monocíclicos
/
Antibacterianos
Limite:
Animals
País/Região como assunto:
Asia
Idioma:
En
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Ano de publicação:
2021
Tipo de documento:
Article