Progressive Pituitary Involvement in a Patient with Localized Granulomatosis with Polyangiitis / 이화의대지
The Ewha Medical Journal
; : 85-88, 2016.
Article
em En
| WPRIM
| ID: wpr-89016
Biblioteca responsável:
WPRO
ABSTRACT
Localized granulomatosis with polyangiitis (loc-GPA) is a milder disease state of GPA restricted to the respiratory tract. Transition from localized form to systemic/generalized disease is predicted to occur in approximately 10% of the patients. We report an unusual case of loc-GPA involving multiple cranial nerves, which in 3 years progressed into systemic disease involving pituitary gland. Initially antineutrophil cytoplasmic antibody (ANCA) was negative, but as symptoms of diabetes insipidus started, ANCA became positive. Clinical course of ANCA negative loc-GPA should be carefully monitored for development of systemic disease. ANCA may be a useful marker for detecting transition from localized to systemic disease.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Hipófise
/
Sistema Respiratório
/
Granulomatose com Poliangiite
/
Anticorpos Anticitoplasma de Neutrófilos
/
Nervos Cranianos
/
Diabetes Insípido
Limite:
Humans
Idioma:
En
Revista:
The Ewha Medical Journal
Ano de publicação:
2016
Tipo de documento:
Article