Research progress of respiratory syncytial virus (RSV) infection and respiratory diseases in infancy / 生理学报
Acta Physiologica Sinica
; (6): 1043-1053, 2021.
Article
em Zh
| WPRIM
| ID: wpr-921309
Biblioteca responsável:
WPRO
ABSTRACT
Lower respiratory tract infection (LRTI) induced by respiratory syncytial virus (RSV) is an important cause of hospitalization for infants. Compared with adults, infants are more likely to cause serious respiratory diseases after RSV infection due to the specific immature airway structure and immune system. The balance of immune resistance and immune tolerance of the host is critical to effective virus clearance and disease control. This paper reviews the relationship between RSV infection and respiratory diseases in infancy, the influence factors of the high pathogenicity of RSV infection in early life, as well as the research progress of anti-RSV therapy, and expands the specific molecular events regulating immune resistance and immune tolerance. We expect to present new ideas for the prevention and treatment of RSV-related respiratory diseases in clinical practice.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Transtornos Respiratórios
/
Vírus Sinciciais Respiratórios
/
Infecções Respiratórias
/
Infecções por Vírus Respiratório Sincicial
Limite:
Humans
/
Infant
Idioma:
Zh
Revista:
Acta Physiologica Sinica
Ano de publicação:
2021
Tipo de documento:
Article