The ATP Level in the mPFC Mediates the Antidepressant Effect of Calorie Restriction / 神经科学通报·英文版
Neuroscience Bulletin
; (6): 1303-1313, 2021.
Article
em En
| WPRIM
| ID: wpr-922625
Biblioteca responsável:
WPRO
ABSTRACT
Food deprivation can rescue obesity and overweight-induced mood disorders, and promote mood performance in normal subjects. Animal studies and clinical research have revealed the antidepressant-like effect of calorie restriction, but little is known about the mechanism of calorie restriction-induced mood modification. Previous studies have found that astrocytes modulate depressive-like behaviors. Inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is the predominant isoform in mediating astrocyte Ca
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Trifosfato de Adenosina
/
Córtex Pré-Frontal
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Camundongos Knockout
/
Restrição Calórica
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Antidepressivos
Limite:
Animals
Idioma:
En
Revista:
Neuroscience Bulletin
Ano de publicação:
2021
Tipo de documento:
Article