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Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Article em En | WPRIM | ID: wpr-929047
Biblioteca responsável: WPRO
ABSTRACT
At present, endometriosis remains a worldwide health burden, with the main symptoms of dysmenorrhea, chronic pelvic pain, and infertility, markedly reducing the quality of life (de Ziegler et al., 2010). Although there is no proof that the disease is associated with high mortality, this disorder can significantly contribute to the deterioration of women's general well-being (McPeak et al., 2018). The main current treatment for endometriosis is surgery to remove endometriotic lesions; however, the recurrence rate following surgical treatment is as high as 21.5% at two years and 40.0%‍-‍50.0% at five years post-surgery (Koga et al., 2015). To prevent recurrence, adjuvant treatment with drugs after surgery is recommended to prolong relapse-free intervals. However, it is inconvenient for patients to continuously use such medications in terms of adverse effects and cost (Turk, 2002).
Assuntos
Texto completo: 1 Índice: WPRIM Assunto principal: Qualidade de Vida / Recidiva / Regulação para Cima / Telomerase / Antígeno Ki-67 / Endometriose / Endométrio Limite: Female / Humans Idioma: En Revista: J. Zhejiang Univ., Sci. B (Internet) Ano de publicação: 2022 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Qualidade de Vida / Recidiva / Regulação para Cima / Telomerase / Antígeno Ki-67 / Endometriose / Endométrio Limite: Female / Humans Idioma: En Revista: J. Zhejiang Univ., Sci. B (Internet) Ano de publicação: 2022 Tipo de documento: Article