Application and research progress of in situ gel for local treatment of periodontitis / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 365-375, 2022.
Article
em Zh
| WPRIM
| ID: wpr-929479
Biblioteca responsável:
WPRO
ABSTRACT
@#Recently, in situ gel has been widely used as a local delivery system for periodontitis treatment because of its lesion injectability, local drug depot function, and drug sustained-release effect.Different therapeutic purposes can be achieved by loading different types of drugs such as antibiotics, bioactive factors, etc.In this review, different types of in situ gel with temperature-sensitive, ion-sensitive, pH-sensitive and solvent-exchanged characteristics were introduced for their applications and limitations in the delivery of drug for periodontitis;and the elimination of periodontal inflammation, periodontal tissue repair and the long-term role after loading microsphere achieved by the in situ gel system were also reviewed.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of China Pharmaceutical University
Ano de publicação:
2022
Tipo de documento:
Article