Research progress of human cytomegalovirus in escaping from the host interferon response / 中华实用儿科临床杂志

ABSTRACT

The human cytomegalovirus (HCMV) infection is widespread in the world, which mainly affects people with an insufficient immunity.Interferon is an important member involved in the innate immune, which is of great significance in the early antiviral response.Owing to the huge genome, HCMV expresses various proteins that resist the host immune response effectively.Moreover, HCMV also exploits host cells to resist the immune response of interferon, thus escaping from the host immune response and establishing a latent infection.This study aims to review the research progress of HCMV in escaping from the host interferon response.