Research advances on the characteristics of fibroblast in keloid / 中华烧伤杂志
Chinese Journal of Burns
; (6): 590-594, 2022.
Article
em Zh
| WPRIM
| ID: wpr-940966
Biblioteca responsável:
WPRO
ABSTRACT
In re-cent 20 years, the development of cell biology technology has promoted the research of keloid. Keloid fibroblasts (KFbs) are the main effector cells in keloid, which are closely related to the occurrence and development of keloid. It is significantly different in terms of biological characteristics and gene expression between KFbs and normal fibroblasts. This articles reviews the characteristics of KFbs from multiple perspectives, describing its biological character- istics in details including microstructures, metabolic character- istics, and proliferation properties, and introducing the main characteristics of heterogeneity and genomics of KFbs. The further research on KFbs will help to elucidate the pathogenesis of keloids and provide valuable strategies for the prevention and treatment of keloids.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Fibroblastos
/
Queloide
Limite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Burns
Ano de publicação:
2022
Tipo de documento:
Article