Otological and hearing characteristics in children with Turner syndrome / 中华耳鼻咽喉头颈外科杂志
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
; (12): 590-595, 2021.
Article
em Zh
| WPRIM
| ID: wpr-942485
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To explore the otological and hearing characteristics in children with Turner syndrome (TS), to determine risk factors of hearing loss, and to discuss algorithms for future surveillance.Methods:
The clinical data of otolaryngology in children with TS from January 2018 to April 2020 were reviewed retrospectively. A total of 46 female children with TS, aged from 5 to 18 years were enrolled. Karyotypes included 17 cases (37.0%) of monosomy, 16 cases (34.7%) of mosaicism, and 13 cases (28.3%) of abnormal X chromosome structures. The otoscopic characteristics, audiological performance, and otologic diagnoses were evaluated. Multivariate logistic regression and Mann-Whitney U test were used for statistical analysis.Results:
The most common otologic comorbidity was otitis media with effusion (OME), including 20 cases (43.5%) with 33 ears (35.9%). 14 cases (30.4%) were diagnosed with hearing loss. The regression analysis revealed that the age (OR=1.345, 95%CI 1.072-1.760) and comorbidity of OME (OR=9.460, 95%CI 2.065-60.350) were risk factors associated with hearing loss. In TS with OME, when compared with the mean air conduction threshold, the hearing loss of the group with pars flaccida retractions was significantly higher ((24.3±13.8) dB HL vs. (14.4±4.2) dB HL, U=59.500, P=0.008) than that of the group with none retractions.Conclusion:
OME and hearing loss are common in children with TS. As age increases or suffers from OME, the risk of hearing loss increases.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Síndrome de Turner
/
Otite Média com Derrame
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Estudos Retrospectivos
/
Audição
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Testes Auditivos
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Child
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Female
/
Humans
Idioma:
Zh
Revista:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2021
Tipo de documento:
Article